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REPRODUCTIVE IMMUNOLOGY TESTING

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Reproductive immunology is a field of medicine that studies the interaction between the immune system and the reproductive system. Here are some tests, treatments, and research in reproductive immunology:

Tests

These include:

  • Reproductive immunophenotype (RIP): Measures NK cells to see if they are abnormally elevated and causing an immune response to the embryo
  • Antinuclear antibodies (ANA) tests: Checks for high levels of antibodies that can complicate pregnancy
  • Antiphospholipid antibodies (APA) tests: Looks for proteins that can increase the risk of blood clots or pregnancy loss
  • Thrombophilia tests: Determines the likelihood of blood clots in the placenta and womb

DQ alpha testing: Measures whether a couple’s DNA is too closely matched

  • Blood tests: Measures antibodies in the blood associated with infertility and miscarriage

Treatments may include,

  • Vitamin D supplements for vitamin D deficiency
  • Blood thinners for patients at increased risk of thrombophilia
  • Immunotherapy for preventing rejection of embryos.

Who Should Opt for Reproductive Immunology Testing:

  1. Women with recurrent miscarriages or failed IVF attempts.

  2. Individuals with autoimmune disorders affecting fertility.

  3. Couples with unexplained infertility despite normal test results.

  4. Women with a history of preterm birth or pregnancy complications.

  5. Those with known or suspected immune system-related fertility issues.

Benefits of Reproductive Immunology Testing:

  1. Identifies immune system factors affecting implantation or pregnancy.

  2. Helps tailor personalized treatment plans to improve IVF outcomes.

  3. Detects autoimmune diseases or immune responses to sperm/embryos.

  4. May reduce the risk of miscarriage through targeted therapies.

  5. Provides insights into unexplained infertility, offering hope for success.